Hepatitis C FAQ. Book 2.
The Treatment

HepCBC - HEPV-L, Febuary 2012

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Part 3: Conventional Medicine

• 3.1.0 Standard treatment
• 3.1.1 Pegylated Interferon, Ribavirin and a Protease Inhibitor Combined
• 3.1.2 Side effects and other considerations
• 3.1.3 Is treatment worth it?
• 3.1.4 When is interferon treatment not indicated?
• 3.1.5 Interferon Breakthrough, Non-response and Relapse
• 3.1.6 Re-treatment
• 3.1.7 Transplant and post-transplant treatment
• 3.1.8 Spontaneous Clearance
• 3.2.0 Interferons
• 3.2.1 Interferon Monotherapy
• 3.2.2 Pegylated Interferon
• 3.2.2a Pegylated Intron A (Peg-Intron A)
• 3.2.2b Peginterferon Alpha-2a (Pegasys)
• 3.2.3a Consensus Interferon
• 3.2.3b Alferon
• 3.2.3c Omega Interferon
• 3.2.3d Albuferon
• 3.2.3e Belerofon
• 3.2.3f Maxygen
• 3.2.3g Locteron
• 3.2.3h PEG-interferon lambda (IL-29)
• 3.2.3i Glycoferon
• 3.2.3j IFN alpha-2b XL (Medusa IFN)
• 3.2.3k ViraferonPeg
• 3.2.3l Oral Interferon
• 3.3.0 Treatment strategies
• 3.3.1 Dosage
• 3.3.1a Mega Dosing
• 3.3.1b Maintenance Dosing
• 3.3.1c Induction Dosing
• 3.3.2 Early Treatment
• 3.3.3 Longer Treatment
• 3.3.4.Retreatment
• 3.4.0 Iron Reduction Therapy

Part 4: Research

• 4.0.1 Hepatitis C treatments in current clinical development
• 4.1.0 HCV Direct-Acting Antivirals
• 4.1.1 Protease Inhibitors
• 4.1.1a PF-03491390 (IDN-6556)
• 4.1.1b ITMN-191
• 4.1.1c TMC435
• 4.1.1d Vaniprevir (MK-7009)
• 4.1.1e Narlaprevir (SCH-900518)
• 4.1.1f PHX1766
• 4.1.1g BI 201335
• 4.1.1h ACH-1625
• 4.1.1i AVL-192
• 4.1.1j Ritonavir (ABT-450)
• 4.1.1k BMS-791325
• 4.1.1l MK-5172
• 4.1.2 Polymerase Inhibitors
• 4.1.2a R7128, R1626, GS-6130, GS-7851, GS-7977, PSI-938
• 4.1.2b MK-0608, MK-3281
• 4.1.2c Vertex Polymerase Inhibitors
• 4.1.2d Tegobuvir (GS-9190)
• 4.1.2e Filibuvir (FBV-formerly PF 00868554)
• 4.1.2f ABT-333, ABT-072
• 4.1.2g Setrobuvir (ANA598)
• 4.1.2h BI 207127
• 4.1.2i INX-189
• 4.1.2j TMC649128
• 4.1.2k Other polymerase inhibitors of interest
• 4.1.3 NS5A Inhibitors
• 4.1.3a BMS-790052
• 4.1.3b A-689
• 4.1.3c AZD7295
• 4.1.3d PPI-461 and PPI-668
• 4.1.3e Achilllion’s NS5A Inhibitor
• 4.1.3f IDX719
• 4.1.4 Other Direct-Acting Antivirals
• 4.1.4a Helicase Inhibitors
• 4.1.4b IRES Inhibitors
• 4.1.4c RNAi-Based Antisense Therapies
• 4.1.4d Entry Inhibitors
• 4.1.4e Cyclophilin Inhibitors
• 4.1.4f BIT225
• 4.1.5 Direct-Acting Antiviral Combos
• 4.1.5a Protease-Polymerase Combos
• 4.1.5b Danoprevir + Ritonavir + PegIFN/RBV
• 4.1.5c Clemizole
• 4.1.5d BMS-790052 Combos
• 4.1.5e GS-7977 + PSI-938
• 4.1.5f ABT-450 + ABT-333
• 4.1.5g IDX184 + IDX375
• 4.2.0 Other Therapies
• 4.2.1 Taribavirin (Viramidine)
• 4.2.2 Zadaxin (Thymosin)
• 4.2.3 Amantadine
• 4.2.4 Alinia (Nitazoxanide)
• 4.2.5 Celgosivir (MX-3253)
• 4.2.6 HCV Monoclonal Antibodies (mAb’s)
• 4.2.7 Toll-like Receptor Agonists IMO-2125, ANA773, SD-101
• 4.2.8 Interferon Alpha Gene Therapy
• 4.2.9 Oglufanide
• 4.2.10 NOV-205
• 4.2.11 JKB-122
• 4.2.12 CB5300
• 4.2.13 MitoQ
• 4.2.14 CTS-1027
• 4.2.15 Interleukins
• 4.2.16 UDCA (ursodeoxycholic acid)
• 4.2.17 Rosiglitazone
• 4.2.18 CF102
• 4.2.19 SCY-635
• 4.2.20 Fluvastatin
• 4.3.0 Vaccines
• 4.3.1 ChronVac
• 4.3.2 Chiron Vaccine
• 4.3.3 Chimigen
• 4.3.4 VIDO Vaccine
• 4.3.5 Toray Vaccine
• 4.3.6 TG4040 Vaccine
• 4.3.7 Intercell vaccine IC41
• 4.3.8 Kurume peptide vaccine
• 4.3.9 Tarmogen (GI-5005)
• 4.4.0 Hepatitis C Treatments in Current Clinical Development

Part 5: Alternative Medicine

• 5.0.0 Known Herb-Drug Interactions
• 5.0.1 Acupuncture
• 5.0.2 Chiropractic
• 5.0.3 Energy Healing
• 5.0.4 Reflexology
• 5.0.5 Homeopathy
• 5.0.6 Reticulose
• 5.0.7 Traditional Chinese Medicine (TCM)
• 5.0.8 Ozone Therapy
• 5.1.0 Herbal Treatments and Vitamins
• 5.1.1 Kombucha Tea
• 5.1.2 Reishi/Shitake Mushrooms
• 5.1.3 Dandelion
• 5.1.4 Milk Thistle
• 5.1.5 Artichoke
• 5.1.6 Licorice Root
• 5.1.7 Spirulina
• 5.1.8 Garlic
• 5.1.9 Thymic Factors
• 5.1.10 Vitamin C
• 5.1.11 Vitamin B12
• 5.1.12 Vitamin E
• 5.1.13 Natural Interferon Boosters
• 5.1.14 Other Herbs or Vitamins
• 5.1.15 Grapefruit
• 5.1.16 Water
• 5.2.0 Exercise
• 5.3.0 Stress Management
• 5.4.0 Positive Attitude
• 5.5.0 Tai Chi/Chi Kung/Yoga/Meditation
• 5.5.1 Tai Chi
• 5.5.2 Yoga
• 5.6.0 Other Ways to Keep Yourself Healthy

Part 6: Nutrition

• 6.1.0 What Should I Do About Nutrition?
• 6.1.1 Foods to Avoid
• 6.2.0 Nutrition and Cirrhosis
• 6.3.0 Coffee, Tea, Caffeine and Other Stimulants
• 6.4.0 Salt

Book 1. The Basics

Book 3. Living with HCV

 

 

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Old links:

3.1.2b Peginterferon Alpha-2a (Pegasys)
4.0.3 Energy healing (Reiki, Hands of Light, Touch Therapy etc)
4.0.6 Reticulose